From discovery to design, we interrogate and reprogram T cell states to enhance ovarian function, restore fertility, and outsmart ovarian tumors.
Located in the University of Florida College of Veterinary Medicine, the Bafor Lab investigates how T cells—particularly CD8⁺ and double-negative T cells (cDNTs)—adapt within reproductive tissues to maintain immune balance and fertility.
Our research connects fundamental immunology with translational design, uncovering how tolerance is built, how it breaks in autoimmune ovarian failure, and how those same molecular programs can be re-engineered to target ovarian tumors.
We blend in vivo experimentation, single-cell and spatial profiling, and immune engineering to decode and redesign the immune circuits that protect reproductive health. Through these efforts, the Bafor Lab aims to transform how we understand and treat infertility and ovarian cancer—building a foundation where immunity and reproduction meet innovation.
